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Getting started4 months ago
Installation | Overview of the workflow | Loading PKML models | Specifying model parameters for analysis | Specifying model outputs for analysis | Running one-at-a-time analyses (local and uncertainty analysis) | Running the Morris (global) sensitivity method | Running variance-based Global Sensitivity Analyses (Sobol and EFAST) | Using the graphical user interface and R script generation | Next steps
Mathematical overview of variance-based methods4 months ago
Mathematical derivation | Computation of variance-based sensitivity indices | Homma & Saltelli (Sobol) | EFAST | References
Midazolam DDI example4 months ago
Background | Parameters analyzed | Loading the package and simulations | Specifying the input parameters | Specifying the model output | Running the sensitivity analyses | Interpreting the results
UV filter formulation example4 months ago
Parameters analyzed | Loading the package and simulation | Specifying the input parameters | Specifying the model output | Running the sensitivity analyses | Interpreting the results